Stories about Science

Promising Results for Pain and Neuroprotection

2 Articles

Studies indicate that cannabinoids may significantly alleviate chronic pain and enhance neuroprotection, expanding cannabis use in medical care.

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Using Cannabis Compounds to Improve Sleep

2 Articles

Cannabinoids like THC, CBD, and CBN show promise for improving sleep by interacting with the endocannabinoid system, but finding the right product and dose is crucial for avoiding unwanted side effects.

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Study Reveals CBN's Potential in Neuroprotection

2 Articles

Salk Institute researchers have discovered that CBN, a lesser-known cannabinoid with neuroprotective properties, could lead to future therapies for neurodegenerative diseases and brain injury prevention. The search for effective treatments for neurodegenerative diseases has long been a challenge, particularly as the global population ages and the prevalence of conditions like Alzheimer’s and Parkinson’s continues to rise. However, recent research from the Salk Institute offers a glimmer of hope, focusing on a lesser-known cannabinoid, cannabinol (CBN), and its potential to protect the brain against aging and neurodegeneration.

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Intensified Dreams and Symptoms After Quitting

10 Articles

Unveiling marijuana withdrawal's multifaceted nature, this article explores its interplay with neurobiology, psychology, and treatment strategies for recovery.

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Recently added Resources about Science

CB1R expression in brain and spinal cord regions, with levels from low to high in green.

Frontiers

Cannabinoid Therapeutics in Chronic Neuropathic Pain: From Animal Research to Human Treatment

26min read

Despite the importance of pain as a warning physiological system, chronic neuropathic pain is frequently caused by damage in the nervous system, followed by persistence over a long period, even in the absence of dangerous stimuli or after healing of injuries.

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Cannabis plant - At Roboexotica, Vienna, 2014

Marijuana Moment

Cannabis Treatment Reduces Chronic Nerve Pain With ‘Minimal To No Side Effects,’ New Scientific Review Finds

4min read

A newly published review of research on marijuana and chronic nerve pain concludes that treatment with cannabinoids offers “significant relief from chronic pain” with “minimal to no side effects”—potentially providing patients a “life-changing alternative” to conventional pharmaceuticals.

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As a library, the National Library of Medicine (NLM) provides access to scientific literature. Inclusion in an NLM database does not imply endorsement of, or agreement with, the contents by NLM or the National Institutes of Health.

National Center for Biotechnology Information

Cannabis and Mood Disorders

17min read

The present review will provide an overview of the neurobiology, epidemiology, clinical impact, and treatment of cannabis use disorder (CUD) in mood disorders. Patients with mood disorders including major depressive disorder (MDD) and bipolar disorder (BD) have higher rates of cannabis use, and CUD compared to the general population. Reasons for this association are not clear, nor are the putative therapeutic effects of cannabis use, or its components delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), in these illnesses. The evidence surrounding treatments for patients with this comorbidity is lacking, with more support for psychotherapeutic treatments compared with pharmacological treatments.

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Flowchart of study selection for qualitative synthesis: 3,262 records identified, 78 studies included, with exclusion reasons.

Frontiers

Cannabis use and mood disorders: a systematic review

24min read

Problematic cannabis use is highly prevalent among people with mood disorders. This underscores the need to understand the effects of cannabis and cannabinoids in this population, especially considering legalization of recreational cannabis use.

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A person laying in a bed under a blanket.

The Weed Blog

Understanding Cannabis And Sleep: THC, CBD, And CBN Explained

3min read

Cannabis products are being used for sleep more frequently as cannabis legalization spreads. Learn more about cannabis and sleep here.

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ScienceDirect

Fragment-based drug discovery and biological evaluation of novel cannabinol-based inhibitors of oxytosis/ferroptosis for neurological disorders

39min read

The oxytosis/ferroptosis regulated cell death pathway is an emerging field of research owing to its pathophysiological relevance to a wide range of neurological disorders, including Alzheimer's and Parkinson's diseases and traumatic brain injury.

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